The thicker the acrylic, the greater the interaction between light and the artwork.¼” acrylic is a fantastic all-purpose solution that balances cost with performance. 3/8” acrylic is however recommended for signature pieces installed in prominent spaces like lobbies or entrances, or conference rooms. 1/8” non-glare polycarbonate panels with ¼” acrylic back panels are standard for changeable acrylic pieces.